Hepatocyte Growth Factor-Secreting Mesothelial Cell Sheets Suppress Progressive Fibrosis in a Rat Model of CKD.

Affiliation

Institute of Advanced Biomedical Engineering and Science, and [Email]

Abstract

Although hepatocyte growth factor (HGF) has antifibrotic effects and is involved in angiogenesis and vasodilation, systemic administration of HGF to prevent kidney fibrosis is not a feasible strategy for suppressing interstitial fibrosis in patients with CKD.

Keywords

HGF,cell sheet,chronic kidney disease,fibrosis,obstructive nephropathy,