Heterogeneous early immune responses to the S. aureus EapH2 antigen induced by gastrointestinal tract colonisation impact the response to subsequent vaccination.

Affiliation

Jenner Institute, University of Oxford, Centre for Cellular and Molecular Physiology, Oxford, UK. Electronic address: [Email]

Abstract

S. aureus is a pathogen to which individuals are exposed shortly after birth, with immune responses to S. aureus increasing during childhood. There is marked heterogeneity between the anti- S. aureus immune responses of different humans, the basis of which is not fully understood.

Keywords

Colonisation,EapH1,EapH2,Mouse,S. aureus,Vaccine,