Identification of galectin-3 as an autoantigen in patients with IgG4-related disease.


Division of Rheumatology, Allergy, & Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass; Ragon Institute of MGH, MIT and Harvard, Cambridge, Mass. Electronic address: [Email]


The antigenic trigger that drives expansion of circulating plasmablasts and CD4+ cytotoxic T cells in patients with IgG4-related disease (IgG4-RD) is presently unknown.


IgG(4)-related disease,autoantibody,autoantigen,galectin-3,plasmablast,