Immune Cell Infiltration May Be a Key Determinant of Long-Term Survival in Small Cell Lung Cancer.


Department of Molecular Medicine, Mayo Clinic, Rochester, Minnesota. Electronic address: [Email]


Although most patients with SCLC die within a few months of diagnosis, a subgroup of patients survive for many years. Factors determining long-term survivorship remain largely unknown. We present the first comprehensive comparative genomic and tumor microenvironment analyses of SCLC between patients with long-term survivorship and patients with the expected survivorship.


Antitumor immunity,Microenvironment,Neuroendocrine,SCLC,TIL,