Influence of Dexamethasone on O-(2-[18F]-Fluoroethyl)-L-Tyrosine Uptake in the Human Brain and Quantification of Tumor Uptake.

Affiliation

Institute of Neuroscience and Medicine (INM-3, INM-4; INM-5; INM-11), Forschungszentrum Jülich, 52425, Jülich, Germany. [Email]

Abstract

O-(2-[18F]fluoroethyl)-L-tyrosine ([18F]FET) is an established positron emission tomography (PET) tracer for brain tumor imaging. This study explores the influence of dexamethasone therapy on [18F]FET uptake in the normal brain and its influence on the maximum and mean tumor-to-brain ratio (TBR).

Keywords

Amino acids,Brain tumors,Dexamethasone,FET,PET,Tumor-to-brain ratio,[18F]Fluoroethyltyrosine,

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