Interleukin-18 serum levels in sepsis: Correlation with disease severity and inflammatory markers.


Magdalena Mierzchala-Pasierb


Department of Medical Biochemistry, Wroclaw Medical University, Chalubinskiego 10, 50-368 Wroclaw, Poland. Electronic address: [Email]


Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection and a syndrome shaped by pathogen and host factors with characteristic that evolve over time. The study was conducted to evaluate the prognostic and discriminative value of IL-18 assessment in comparison to PCT, CRP, WBC in early stage of sepsis and septic shock.


Biomarker,Interleukin 18,Sepsis,Septic shock,

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