Investigating propofol-sufentanil interaction using clinical endpoints and processed electroencephalography: a prospective randomized controlled trial.

Affiliation

Pediatric Anesthesia Unit, Department of Anesthesiology, Sophia Children's Hospital, Erasmus University Medical Center, Rotterdam, The Netherlands - [Email]

Abstract

Propofol and sufentanil target controlled infusion technology is used with increasing frequency. Drug interaction modelling, using clinical endpoints and processed electroencephalography helps determine optimal drug concentrations to assure adequate anesthesia.