Investigating propofol-sufentanil interaction using clinical endpoints and processed electroencephalography: a prospective randomized controlled trial.


Pediatric Anesthesia Unit, Department of Anesthesiology, Sophia Children's Hospital, Erasmus University Medical Center, Rotterdam, The Netherlands - [Email]


Propofol and sufentanil target controlled infusion technology is used with increasing frequency. Drug interaction modelling, using clinical endpoints and processed electroencephalography helps determine optimal drug concentrations to assure adequate anesthesia.