LncRNA H19 promotes epithelial mesenchymal transition and metastasis of esophageal cancer via STAT3/EZH2 axis.

Affiliation

Department of Thoracic Surgery, The Second Xiangya Hospital of Central South University, Changsha 410011, PR China. Electronic address: [Email]

Abstract

Long non-coding RNA H19 (lncRNA H19) has been widely reported in esophageal cancer (EC), and previous study had found that lncRNAH19 was up-regulated in EC and promoted cell proliferation and metastasis. However, the mechanism still needs further studied.

Keywords

EMT and metastasis,EZH2,Esophageal cancer,STAT3,lncRNA H19,