Manipulation of Nephron-Patterning Signals Enables Selective Induction of Podocytes from Human Pluripotent Stem Cells.


Department of Kidney Development, Institute of Molecular Embryology and Genetics, and [Email] [Email]


Previous research has elucidated the signals required to induce nephron progenitor cells (NPCs) from pluripotent stem cells (PSCs), enabling the generation of kidney organoids. However, selectively controlling differentiation of NPCs to podocytes has been a challenge.


cell resource,directed differentiation,kidney development,nephron patterning,pluripotent stem cell,podocyte,