MiR-30c/PGC-1β protects against diabetic cardiomyopathy via PPARα.

Affiliation

Division of Cardiology and Hubei Key Laboratory of Genetics and Molecular Mechanisms of Cardiological Disorders, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China. [Email]

Abstract

Metabolic abnormalities have been implicated as a causal event in diabetic cardiomyopathy (DCM). However, the mechanisms underlying cardiac metabolic disorder in DCM were not fully understood.

Keywords

Cardiac metabolism,Diabetic cardiomyopathy,PGC-1β,miR-30c,