Molecular damage and responses of oral keratinocyte to hydrogen peroxide.


Department of Stomatology, National Cheng-Kung University Hospital, Tainan, 70101, Taiwan. [Email]


Hydrogen peroxide (H2O2)-based tooth bleaching reagents have recently increased in popularity and controversy. H2O2 gel (3%) is used in a Nightguard for vital bleaching; transient tooth sensitivity and oral mucosa irritation have been reported. Genotoxicity and carcinogenicity have also been significant concerns.


Keratinocyte(s),Molecular genetics,Oxidative stress,Tooth bleaching,Toxicology,