Monitoring the Progression of Chronic Liver Damage in Rats Using [18F]PBR06.


Department of Nuclear Medicine, Xin Hua Hospital Affiliated To Shanghai Jiao Tong University School, No. 1665, Kongjiang Street, Yangpu District, Shanghai, 200092, China. [Email]


Accurate and rapid assessment of liver condition is the key to therapy for hepatitis patients. This study aim is to evaluate the peripheral benzodiazepine receptor (PBR) radioligand [18F]N-fluoroacetyl-N-(2,5-dimethoxybenzyl)-2-phenoxyaniline ([18F]PBR06) as a positron emission tomography (PET) imaging tracer of chronic liver damage in a rat model.


Inflammation,Liver damage,PBR,Positron emission tomography,[18F]PBR06,