Morphological and mechanical stability of bladder cancer cells in response to substrate rigidity.

Affiliation

Institute of Nuclear Physics, Polish Academy of Sciences, PL-31341 Kraków, Poland. Electronic address: [Email]

Abstract

Morphology of cells can be considered as an interplay between the accessibility of substrate anchoring sites, cytoskeleton properties and cellular deformability. To withstand tension induced by cell's environment, cells tend to spread out and, simultaneously, to remodel actin filament organization.

Keywords

Actin cytoskeleton remodeling,Atomic force microscopy,Basement membrane,Cell mechanics,Laminin,Morphological and mechanical stability,Tumor environment,

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