Multifocal Primary Prostate Cancer Exhibits High Degree of Genomic Heterogeneity.

Affiliation

Department of Molecular Oncology, Institute for Cancer Research, Oslo University Hospital-Radiumhospitalet, Oslo, Norway; Norwegian Cancer Genomics Consortium, Oslo, Norway. Electronic address: [Email]

Abstract

Most primary prostate cancers are multifocal with individual tumors harboring different aggressiveness; however, the genomic heterogeneity among these tumors is poorly understood.

Keywords

Exome sequencing,Heterogeneity,Multifocal,Prostate cancer,Somatic mutations,