Naturally occurring NS5A and NS5B resistant associated substitutions in HCV and HCV/HIV patients in iranian population.

Affiliation

Clinical Research Dept, Pasteur Institute of Iran, Tehran, Iran. Electronic address: [Email]

Abstract

The introduction of direct acting antivirals (DAAs) for hepatitis C virus (HCV) treatment promises shorter treatment duration, higher cure rates and fewer side effects. Naturally, occurring Resistance Associated Substitutions (RASs) are major challenge to the success of the HCV antiviral therapy.

Keywords

Direct acting antivirals (DAAs),Hepatitis C virus (HCV),Human immunodeficiency virus (HIV),NS5A,NS5B,Resistance associated substitution (RAS),