Neuro-genetic plasticity of Caenorhabditis elegans behavioral thermal tolerance.


Department of Physics, University of Toronto, Toronto, Canada. [Email]


Animal responses to thermal stimuli involve intricate contributions of genetics, neurobiology and physiology, with temperature variation providing a pervasive environmental factor for natural selection. Thermal behavior thus exemplifies a dynamic trait that requires non-trivial phenotypic summaries to appropriately capture the trait in response to a changing environment. To characterize the deterministic and plastic components of thermal responses, we developed a novel micro-droplet assay of nematode behavior that permits information-dense summaries of dynamic behavioral phenotypes as reaction norms in response to increasing temperature (thermal tolerance curves, TTC).


C. elegans behavior,Computational ethology,Thermal ecology,

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