Nuclear localization of β-catenin and expression of target genes are associated with increased Wnt secretion in oral dysplasia.

Affiliation

Institute for Research in Dental Sciences, Faculty of Dentistry, Universidad de Chile, Santiago, Chile; Advanced Center for Chronic Diseases (ACCDiS), Universidad de Chile, Santiago, Chile. Electronic address: [Email]

Abstract

To evaluate the localization of β-catenin in oral dysplastic cells, the expression of target genes upregulated in oral dysplasia, and the role of Wnt ligands in these events.

Keywords

Cell signaling,Keratinocyte,Oral cancer,Oral dysplasia,Survivin,Wnt,β-Catenin,

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