Oestradiol-releasing Biodegradable Mesh Stimulates Collagen Production and Angiogenesis: An Approach to Improving Biomaterial Integration in Pelvic Floor Repair.


Department of Materials Science Engineering, Kroto Research Institute, University of Sheffield, UK. Electronic address: [Email]


Polypropylene meshes cause severe complications in some patients. Materials that are biomechanically compatible and can better integrate into host tissues are urgently needed.


Angiogenesis,Mesh complications,Oestradiol,Pelvic organ prolapse,Polylactic acid,Stress urinary incontinence,Tissue engineering,