One simple Ir/hydrosilane catalytic system for chemoselective isomerization of 2-substituted allylic ethers.

Affiliation

State Key Laboratory of Organic-Inorganic Composites, College of Chemical Engineering, Beijing University of Chemical Technology, Beijing, 100029, China. [Email]

Abstract

Here, we describe one simple Ir/hydrosilane catalytic system for chemoselective isomerization of 2-substituted allylic ethers. This facile strategy shows high efficiency towards a variety of substrates, including derivatives from bioactive molecules. The substituent at the α position of the olefins is supposed to be critical in retarding the alkene hydrosilylation process and leading the reaction to go through the isomerization pathway.

OUR Recent Articles