Palladium-catalyzed carbonylative synthesis of substituted cyclopentenones from aryl iodides and internal alkynes.

Affiliation

Department of Chemistry, Zhejiang Sci-Tech University, Xiasha Campus, Hangzhou 310018, People's Republic of China. [Email]

Abstract

In this Communication, a palladium-catalyzed carbonylative synthesis of substituted cyclopentenones has been developed. With aryl iodides and internal alkynes as the substrates, via a domino process consisting of a formal Pauson-Khand reaction, good yields of the desired products were obtained. Interestingly, formic acid has been used both as a hydrogen source and a carbon monoxide source in this system.

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