Parkinson's Disease and Parkinsonism.

Affiliation

Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass. Electronic address: [Email]

Abstract

Parkinson's disease is a progressive neurodegenerative disease characterized by tremor and bradykinesia and is a common neurologic ailment. Male sex and advancing age are independent risk factors and, as the population ages, is taking an increasing toll on productivity and medical resources. There are a number of other extrapyramidal conditions that can make the diagnosis challenging. Unlike other neurodegenerative diseases, idiopathic Parkinson's disease has effective treatments that mitigate symptoms. Medications can improve day-to-day function and, in cases where medication does not give a sustained benefit or has significant side effects, treatments like deep brain stimulation result in improved quality of life.

Keywords

Deep brain stimulation,Parkinson's disease,Parkinsonism,Pharmacologic treatment,

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