Antibacterial coating of surgical sutures is a suggested approach to prevent surgical site infections. The aim of this study was to compare the incidence of surgical site infection following the use of polyglactin 910 (Vicryl) and polyglactin 910 coated with triclosan (Vicryl Plus) sutures in dental implant surgery. This single-blind, randomized clinical trial evaluated patients who received three implants in the posterior mandible. Patients were randomly divided into two groups to receive either Vicryl Plus sutures (group 1) or Vicryl sutures (group 2). A total of 320 patients were included in the study (n=160 in each group). Twelve patients (7.5%) in group 1 and 11 patients (6.9%) in group 2 had a surgical site infection. Analysis of the data did not demonstrate any significant difference in the incidence of surgical site infection between the two groups (P=0.5). The incidence of surgical site infection in fresh socket implant placement was higher than that in delayed implant placement, irrespective of the type of suture used (P=0.001). Triclosan-coated Vicryl sutures did not decrease the incidence of surgical site infection in dental implant surgery.