Potential Diagnostic and Prognostic Role of Microenvironment in Malignant Pleural Mesothelioma.


Department of Oncology, University of Torino, Torino, Italy; Interdepartmental Center "G. Scansetti" for the Study of Asbestos and Other Toxic Particulates, University of Torino, Torino, Italy. Electronic address: [Email]


A comprehensive analysis of the immune cell infiltrate collected from pleural fluid and from biopsy specimens of malignant pleural mesothelioma (MPM) may contribute to understanding the immune-evasion mechanisms related to tumor progression, aiding in differential diagnosis and potential prognostic stratification. Until now such approach has not routinely been verified.


Immune checkpoints,Malignant pleural mesothelioma,Myeloid-derived suppressor cells,T-regulatory cells,Tumor-infiltrating lymphocytes,

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