Preventing potential drug-drug interactions through alerting decision support systems: A clinical context based methodology.


Nephrology and Kidney Transplant Research Center, Urmia University of Medical Sciences, Urmia, Iran. Electronic address: [Email]


The effectiveness of the clinical decision support systems (CDSSs) is hampered by frequent workflow interruptions and alert fatigue because of alerts with little or no clinical relevance. In this paper, we reported a methodology through which we applied knowledge from the clinical context and the international recommendations to develop a potential drug-drug interaction (pDDI) CDSS in the field of kidney transplantation.


Adverse drug events,Alert fatigue,Clinical decision support systems,Kidney transplantation,Medication alerting system,Patient safety,Potential drug-drug interaction,

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