Pulmonary arterial hypertension associated with interferon-beta treatment for multiple sclerosis. Case report and literature review.


Onassis Cardiac Surgery Center, Noninvasive Department of Cardiology, Athens, Greece. Electronic address: [Email]


Drug-Induced Pulmonary Arterial Hypertension (PAH) represents a well-known entity, predominantly related to anorexigens. Interferon-β (IFN) is considered to be a drug with a possible risk of inducing PAH. We report a patient with Multiple Sclerosis treated with IFN-β who diagnosed with PAH and her course of disease under specific PAH drug therapy. A review of the literature in IFN-β-induced PAH is provided.


Interferon-β,Multiple sclerosis,Pulmonary arterial hypertension,