Puzzling mRNA: Alternative splicing fine-tunes specificity and function.


University of Copenhagen, BRIC Biotech Research & Innovation Centre, Anders Lund Group, Ole Maaløes Vej 5, 2200, Copenhagen, Denmark. Electronic address: [Email]


In this issue of the Biomedical Journal we discover how alternative splicing might modulate the cell-type specificity and exact function of a ubiquitous purinergic receptor and how the beta blocker propanolol can contribute to breast cancer therapy. Moreover, we learn which culture conditions generate the best vascularisation of tissue engineered bone and which are the clinical features of acute necrotising encephalopathy in adults. Other studies reveal, how laser irradiation can fix fractured all-ceramic dental restorations in situ, and finally that nuclear magnetic resonance holds great potential for the rapid detection of pathogens.


Acute necrotizing encephalopathy,Alternative splicing,P2RX7receptor,Propanolol,Tissue engineering,

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