Quality of life across domains among individuals with treatment-resistant depression.


Department of Psychiatry, University of Utah School of Medicine, Salt Lake City, UT, USA. Electronic address: [Email]


Treatment-resistant depression affects millions of people worldwide and is a leading cause of disability and suicide. Studies of treatment-resistant depression outcomes have traditionally focused on depressive symptoms and functional impairment. Quality of life (QoL) has not been well described. We aimed to measure QoL in individuals with treatment-resistant depression and to determine how QoL was related to traditional measures of symptoms and social functioning.


Bipolar disorder,Childhood adversity,Functional impairment,Major depressive disorder,Quality of life,Treatment-resistant depression,