Resting Coronary Flow Varies With Normal Cardiac Catheter Laboratory Stimuli.


Cardiovascular Division, St Thomas' Hospital Campus, King's College London, United Kingdom. Electronic address: [Email]


Growing evidence supports physiology-guided revascularization, with Fractional Flow Reserve (FFR) the most commonly used invasive measure of coronary blood flow impairment at the time of diagnostic angiography. Recently, there has been growing interest in stenosis severity indices measured at rest, such as Instantaneous Wave Free Ratio (iFR) and the ratio of distal coronary to aortic pressure at rest (resting Pd/Pa). Their reliability may, theoretically, be more susceptible to changes in microvascular tone and coronary flow. This study aimed to assess variability of resting coronary flow with normal catheter laboratory stimuli.


Coronary artery disease,Fractional flow reserve,Instantaneous wave-free ratio,

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