Soft-tissue fat tumours: differentiating malignant from benign using proton density fat fraction quantification MRI.


Department of Molecular Medicine and Surgery, Karolinska Institutet, Solnavägen 1, 171 77, Stockholm, Sweden; Department of Neuroradiology, Karolinska University Hospital, Solna, Stockholm, Sweden. Electronic address: [Email]


To evaluate if quantifying proton density fat fraction (PDFF) would be useful in separating lipoma, atypical lipomatous tumour (ALT) and liposarcoma in the extremities and trunk. In addition, differentiating ALT versus non-classical lipomas using magnetic resonance imaging (MRI)-based fatty acid composition (FAC) and three-dimensional (3D) texture analysis was tested.

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