Spatial characteristics of spontaneous and stimulus-induced individual functional connectivity networks in severe disorders of consciousness.


Institute of Biological and Medical Engineering, Department of Psychiatry and Section of Neuroscience, and Laboratory for Brain-Machine Interfaces and Neuromodulation, Schools of Engineering, Biology & Medicine, Pontificia Universidad Católica, Chile; Wyss Center for Bio and Neuro Engineering, Biotechnology Campus, Genèva, Switzerland. Electronic address: [Email]


Functional connectivity (fcMRI) analyses of resting state functional magnetic resonance imaging (fMRI) data revealed substantial differences between states of consciousness. The underlying cause-effect linkage, however, remains unknown to the present day. The aim of this study was to examine the relationship between fcMRI measures and Disorders of Consciousness (DOC) in resting state and under adequate stimulation.

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