Starting Renal Replacement Therapy: Is It About Time?


Division of Nephrology, Department of Medicine, University of California, San Francisco, California, USA, [Email]


Studies of the timing of end-stage renal disease (ESRD) have primarily defined "early" versus "late" initiation of dialysis using estimated glomerular filtration rate (eGFR)-based criteria. Our objective was to determine the theoretical time that could be spent in chronic kidney disease (CKD) stage 5 prior to reaching a conservative eGFR threshold of 5 mL/min/1.73 m2 compared to the actual time spent in CKD stage 5 by risk factors of interest.


Chronic kidney disease,End-stage renal disease,Timing of dialysis initiation,

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