Supplementary motor area connectivity and dual-task walking variability in multiple sclerosis.


Program in Physical Therapy and Department of Neurology, Wayne State University, Detroit, MI, United States; Division of Physical Therapy, The Ohio State University, Columbus, OH, United States; School of Health and Rehabilitation Sciences, The Ohio State University, Columbus, OH, United States. Electronic address: [Email]


Despite the prevalence of dual-task (e.g., walking while talking) deficits in people with multiple sclerosis (MS), no neuroimaging studies to date have examined neuronal networks used for dual-task processing or specific brain areas related to dual-task performance in this population. A better understanding of the relationship among underlying brain areas and dual-task performance may improve targeted rehabilitation programs. The objective of this study was to examine relationships between neuroimaging measures and clinical measures of dual-task performance, and reported falls in persons with MS.


Dual-task,Multiple sclerosis,Neuroimaging,Supplementary motor area,Walking,