The RNA binding protein HuR influences skeletal muscle metabolic flexibility in rodents and humans.


Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, LA, United States of America. Electronic address: [Email]


Metabolic flexibility can be assessed by changes in respiratory exchange ratio (RER) following feeding. Though metabolic flexibility (difference in RER between fasted and fed state) is often impaired in individuals with obesity or type 2 diabetes, the cellular processes contributing to this impairment are unclear.


Metabolic flexibility,RNA homeostasis,Skeletal muscle,