The fight against multidrug-resistant organisms: The role of ZnO crystalline defects.


Electroceramic Department, Instituto de Cerámica y Vidrio, CSIC, Kelsen 5, 28049 Madrid, Spain; NanoBioMatters Bactiblock, NanoBioMatters Industries S.L., Louis Pasteur 11, 46980 Paterna, Valencia, Spain. Electronic address: [Email]


This article reports the excellent antimicrobial response of nanoparticulate ZnO against multidrug-resistant organisms (MDROs). We demonstrate that the enhanced antimicrobial activity against MDROs depends on the crystalline defects of ZnO. Hence, this work provides insights on the ZnO-microorganism interactions, and we pose combined physico-chemical action mechanisms against resistant bacteria.


Action mechanisms,Antimicrobial properties,MDROs,Nanoparticles,ZnO,

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