The impact of different inclusion decisions on the comprehensiveness and complexity of overviews of reviews of healthcare interventions.


Department of Pediatrics, Alberta Research Centre for Health Evidence, University of Alberta, Edmonton, Canada. [Email]


Overviews of reviews (overviews) compile information from multiple systematic reviews (SRs) to provide a single synthesis of relevant evidence for decision-making. Overviews may identify multiple SRs that examine the same intervention for the same condition and include some, but not all, of the same primary studies. There is currently limited guidance on whether and how to include these overlapping SRs in overviews. Our objectives were to assess how different inclusion decisions in overviews of healthcare interventions affect their comprehensiveness and results, and document challenges encountered when making different inclusion decisions in overviews.


Case series,Knowledge synthesis,Overview of reviews,Systematic review,