The role of chamaejasmine in cellular apoptosis and autophagy in MG-63 cells.


Department of Cardiology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China [Email]


Osteosarcoma (OS) is the most common malignant neoplasm in children and adolescents with a very high propensity for local invasion and poor response to current therapy. Anti-cancer effect of chamaejasmine is newly discovered from Stellera chamaejasmine L. Our study focuses on investigating the effect of chamaejasmine on the cellular apoptosis, proliferation, autophagy, and the underlying mechanisms in MG-63.