Transcranial direct current stimulation in inflammatory bowel disease patients modifies resting-state functional connectivity: A RCT.


Department of Neurology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany. Electronic address: [Email]


Chronic pain is known to be associated with functional and structural changes in the brain. Inflammatory bowel disease (IBD) presents with chronic abdominal pain in almost 35% of all patients. This study investigates structural and functional changes in magnetic resonance imaging (MRI) after transcranial direct current stimulation (tDCS) applied to ameliorate pain in IBD.


Inflammatory bowel disease,Magnetic resonance imaging,Transcranial direct current stimulation,Visceral pain,