H.B. Williams Craniofacial and Cleft Surgery Unit, Montreal Children's Hospital, Division of Plastic and Reconstructive Surgery, McGill University Health Center, 1001 Decarie Boulevard, B05.3310, Montreal, Quebec H4A 3J1, Canada. Electronic address: [Email]
Treacher Collins syndrome is a rare genetic disorder of craniofacial development with a highly variable phenotype. The disorder displays an intricate underlying dysmorphology. Affected patients may suffer life-threatening airway complications and functional difficulties involving sight, hearing, speech, and feeding. Deformation of facial structures produces a characteristic appearance that includes malar hypoplasia, periorbital soft tissue anomalies, maxillomandibular hypoplasia, and ear anomalies. Management requires a specialized craniofacial team, as comprehensive care starts at birth and may require life-long follow-up. Standard craniofacial procedures for bony and soft tissue reconstruction are used. This article outlines current treatment strategies and future concepts for surgical management.