Tumor Formation of Adult Stem Cell Transplants in Rodent Arthritic Joints.

Affiliation

Department of Radiology, Molecular Imaging Program at Stanford (MIPS), Stanford University, 725 Welch Rd, Rm 1665, Stanford, CA, 94305-5654, USA. [Email]

Abstract

While imaging matrix-associated stem cell transplants aimed for cartilage repair in a rodent arthritis model, we noticed that some transplants formed locally destructive tumors. The purpose of this study was to determine the cause for this tumor formation in order to avoid this complication for future transplants.

Keywords

Chondrosarcomas,Fibromyxoid sarcomas,Magnetic resonance imaging,Malignant tumors in vivo,Osteochondral transplants,Stem cell therapy,

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