Virus, Vessel, Victory: A Novel Approach to Tumor Killing.

Affiliation

Ludwig Collaborative Laboratory, Memorial Sloan Kettering Cancer Center, New York, New York. [Email]

Abstract

Ovarian cancer is intimately dependent on aberrant tumor vasculature. A unique therapeutic approach combining a systemic oncolytic virus with a novel vascular-normalizing agent in ovarian cancer demonstrates the potential to enhance antitumor efficacy through improved delivery of the virus and enhanced infiltration of immune cells into the tumors.See related article by Matuszewska et al., p. 1624.

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