Prof Odeh S O
Dr Jimmy E O, Lipton tea and coffee complicate pathogenesis of its induced gastric ulcer with fluctuations in amylase and protein levels(2017)SDRP Journal of Cellular and Molecular Physiology 2(1)p:87-92
Gastric and plasma alpha amylase and proteins concentrations were evaluated in male and female albino rats fed with Lipton tea and coffee induced gastric ulcer. A total of ninety-six male and female albino rats were studied for 28 days. There was no significant difference (p>0.5) in gastric alpha amylase concentrations between the two beverages and the male and female rats. Also there was no significant difference in plasma alpha amylase between Lipton tea and coffee, (P>0.05) and between sexes, (p>0.05). However, the plasma alpha amylase values were very low as compared to control rats without gastric ulcer. There was significant difference in plasma protein concentrations between rats fed with coffee and Lipton tea, (p<0.05) as more proteins concentrations were recorded in coffee feeding than in Lipton tea. Also there was significant difference in plasma protein concentrations in the weekly studies of 7, 14, 21, 28 days (p>0.05). And no significant differences (p>0.05) between the sexes and rats fed with caffeinated and decaffeinated coffee. Cumulatively, both gastric and plasma proteins showed no significant difference, (p>0.5) in their concentrations in Lipton tea and coffee. But there was significant difference (p<0.05) in gastric protein between caffeinated and decaffeinated coffee. Significant differences, (p<0.05) also existed in gastric protein concentrations between 7, 14, 21 and 28 days. Both Lipton tea and coffee induced gastric ulcer, reduced amylase and increased protein concentrations and such may be associated with panccreatitis, kidney disease, multiple myeloma, bone marrow disorder, chronic inflammatory conditions and amyloidosis.
Key words: Amylase, proteins, Lipton tea, coffee, gastric ulcer.
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