Description

Chromatin, the complex structure that results from the interaction between DNA and nuclear proteins, organises the nuclear genome in the restricted space of the nucleus in which diverse processes occur in the absence of internal membranes. as occurs, for instance, within the cytoplasm thanks to organelle membranes. Chromatin structure is highly dynamic allowing the unconstrained but controlled reprogramming of the nuclear processes, such as gene expression, in response to internal and external cues. This is particularly important in plants that, as sessile organisms, have to modify their development and growth depending on the combined action of their own internal signals and the environment.

Chromatin remodeling mechanisms responsible for modifying the structure of chromatin therefore add another layer in the regulation of gene expression decisively contributing to plant phenotypes. Despite the powerful plasticity of chromatin remodeling in controlling gene expression, the organisation of nuclear space is a key element in the maintenance of specific chromatin states during cell division which ensures determination and perpetuation of cell fate. In these two principally antagonistic functions, the recruitment of specific chromatin modifiers to precise target regions within the chromatin represents a decisive role for establishing new transcriptional states.

This Research Topic focuses on recent breakthroughs in our understanding of the complex balance between dynamics and stability of chromatin states. We therefore welcome contributions related to:

- Mitotic maintenance of chromatin states
- Preservation of the chromatin status through S-phase
- Resetting of chromatin states through chromatin re-modelling
- Chromatin rearrangements
- Recruitment of chromatin modifiers through transcription factors and other components of the transcription machinery
- Involvement of RNAs in the recruitment of chromatin modifiers
- Contribution of cis-elements and DNA conformation in the interaction of chromatin modifiers
- Role of chromatin modifications and structure in the binding with chromatin modifiers
- Interactions among different chromatin modifiers